Mushrooms have been a part of human culture and cuisine for centuries, with their earliest recorded usage dating back to ancient civilizations such as China, Egypt, and Mexico. Chinese medicine recognized their medicinal properties, Egypt considered them a delicacy, and the Aztecs believed in their spiritual properties. Mushrooms were also used in ancient Greece and Rome, and continue to be popular today in various forms. This article explores the historical roots of mushroom usage and their significance in human culture.